In order to graduate, a student must successfully complete 24 units of credit, which include the following:
| Theology | 4.0 credits * |
| English | 4.0 credits |
| Mathematics | 3.0 credits |
| Science | 2.0 credits |
| Social Studies (including American History) | 2.0 credits |
| Physical Education | 1.5 credits |
| Consumer Economics | 0.5 credit |
| Fine Arts | 0.5 credit |
| Health | 0.5 credit |
| Speech | 0.5 credit |
| Electives | 5.5 credits |
| U.S. Constitution Test | passing score |
| Senior Service Project | successful completion |
* For transfer students, a theology credit is required for each semester they are enrolled at Mater Dei.